Lamberti, Gaetano; Cascone, Sara; Titomanlio, Giuseppe An engineering approach to biomedical sciences: advanced testing methods and pharmacokinetic modeling Journal Article Translational Medicine@ UniSa, 4 , pp. 34–38, 2012. Abstract | BibTeX | Tags: In silico, in-silico, in-vitro, in-vivo, Pharmacokinetics, testing methods @article{Lamberti2012b,
title = {An engineering approach to biomedical sciences: advanced testing methods and pharmacokinetic modeling},
author = { Gaetano Lamberti and Sara Cascone and Giuseppe Titomanlio},
year = {2012},
date = {2012-01-01},
journal = {Translational Medicine@ UniSa},
volume = {4},
pages = {34--38},
publisher = {Universit},
abstract = {In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical systems (in-vitro techniques), as well as the proposal and the testing of mathematical models to describe the pharmacokinetics (in-silico techniques) are reported with the aim of pointing out methodologies and tools able to reduce the need of expensive and ethical problematic in-vivo measurements.},
keywords = {In silico, in-silico, in-vitro, in-vivo, Pharmacokinetics, testing methods},
pubstate = {published},
tppubtype = {article}
}
In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical systems (in-vitro techniques), as well as the proposal and the testing of mathematical models to describe the pharmacokinetics (in-silico techniques) are reported with the aim of pointing out methodologies and tools able to reduce the need of expensive and ethical problematic in-vivo measurements. |
