Veronica De Simone

PhD student

+39.089.968291

Theses

PhD thesis (in progress)

Veronica De Simone, Relevant phenomena and process parameters in granulation for manufacturing of pharmaceutical, nutraceutical and zootechnical products.

Master thesis

Veronica De Simone, Analisi dei principali parametri operativi per il processo di granulazione ad umido, Laurea Magistrale in Ingegneria Chimica, student ID: 0622200048, defence date: 30/07/2015, supervisor(s): Prof. Ing. Gaetano Lamberti, Prof. Ing. Anna Angela Barba, assistant supervisor(s): Ing. Annalisa Dalmoro, thesis extract, full thesis

Tesi triennale

Veronica De Simone, Una tecnica in-vitro per la realizzazione e l’analisi del gelpaving di stent coronarici, Laurea in Ingegneria Chimica, student ID: 610200286, defence date: 22/02/11, supervisor(s): Prof. Ing. Gaetano Lamberti, Prof. Ing. Anna Angela Barba, thesis extract, full thesis

Publications

2018

Simone, Veronica De; Caccavo, Diego; Dalmoro, Annalisa; Lamberti, Gaetano; D'Amore, Matteo; Barba, Anna Angela

Inside the Phenomenological Aspects of Wet Granulation: Role of Process Parameters Book Chapter

In: Kyzas, George (Ed.): Chapter 5, IntechOpen, 2018, ISBN: 978-1-78984-308-8.

Abstract | Links | BibTeX | Tags: Granulation, HPMC, Mathematical modeling

@inbook{Simone}2018c,

title = {Inside the Phenomenological Aspects of Wet Granulation: Role of Process Parameters},

author = {Veronica {De Simone} and Diego Caccavo and Annalisa Dalmoro and Gaetano Lamberti and Matteo D'Amore and Anna Angela Barba},

editor = {George Kyzas},

url = {https://www.intechopen.com/books/granularity-in-materials-science/inside-the-phenomenological-aspects-of-wet-granulation-role-of-process-parameters},

doi = {10.5772/intechopen.79840},

isbn = {978-1-78984-308-8},

year  = {2018},

date = {2018-10-24},

publisher = {IntechOpen},

chapter = {5},

abstract = {Granulation is a size-enlargement process by which small particles are bonded, by means of various techniques, in coherent and stable masses (granules), in which the original particles are still identifiable. In wet granulation processes, the powder particles are aggregated through the use of a liquid phase called binder. The main purposes of size-enlargement process of a powder or mixture of powders are to improve technological properties and/or to realize suitable forms of commercial products. A modern and rational approach in the production of granular structures with tailored features (in terms of size and size distribution, flowability, mechanical and release properties, etc.) requires a deep understanding of phenomena involved during granules formation. By this knowledge, suitable predictive tools can be developed with the aim to choose right process conditions to be used in developing new formulations by avoiding or reducing costs for new tests. In this chapter, after introductive notes on granulation process, the phenomenological aspects involved in the formation of the granules with respect to the main process parameters are presented by experimental demonstration. Possible mathematical approaches in the granulation process description are also presented and the one involving the population mass balances equations is detailed.},

keywords = {Granulation, HPMC, Mathematical modeling},

pubstate = {published},

tppubtype = {inbook}

}